姓 名:刘双江
性 别:男
职位职称:中国科学院微生物研究所副所长、研究员、博士生导师
工作单位:中国科学院微生物研究所
学 历:本科
专 业:生物系微生物生化专业
学 校:河北大学
学 历:硕士
专 业:环境科学系农业微生物专业
学 校:浙江农业大学
学 历:博士
专 业:环境工程系水处理专业
学 校:清华大学
学 历:博士后
专 业:糖生物学及糖生物技术
学 校:亚洲分子生物学组织
1991-1995中科院微生物所,先后任助理研究员、副研究员
1995-1996德国明斯特大学微生物研究所,高级访问学者、博士后
1996-1997日本筑波市国立生命工学研究所,高级访问学者
1997-1998美国James Madison大学生物系,博士后
1998-2001赴德国Muenster大学微生物研究所工作
2001年至今中科院微生物研究所,研究员、博士研究生导师
生物技术
论文:
英文论文:
2008
·1.X-Y Liu,B-J Wang,C-Y Jiang,and S-J Liu.2008.Ornithinimicrobium pekingense sp.nov.,isolated from activated sludge.Int.J.Syst.Evol.Microbiol.58:116-119
·2.Zhi-Pei Liu,Bao-Jun Wang,Xing-Yu Liu,Xin Dai,Ying-Hao Liu and Shuang-Jiang Liu.2008.Paracoccus marinus sp.nov.,isolated from sediment of South China Sea.Int.J.Syst.Evol.Microbiol.58:257-261
·3.Yan Huang,Ke-Xin Zhao,Xi-Hui Shen,Cheng-Ying Jiang,and Shuang-Jiang Liu.2008.Genetic and biochemical characterization of a 4-hydroxybenzoate hydroxylase from Cornebacterium glutamicum.Appl.Microbiol.Biotechnol.78:75-83
·4.Ya-Jun Liu,Pan-Pan Li,Ke-Xin Zhao,Cheng-Ying Jiang,Harold L Drake,Shuang-Jiang Liu.2008.Corynebacterium glutamicum contains 3-deoxy-D-arabino-heptulosonate 7-phosphate synthases that display novel biochemical features.Appl.Environ.Microbiol.74:5497-5503.
·5.Cheng-Ying Jiang,Ying Liu,Yan-Yang Liu,Xiao-Yan You,Xu Guo,and Shuang-Jiang Liu.2008.Alicyclobacillus ferrooxydans sp.nov.a novel ferrous-oxidizing bacterium from solfataric soil.Submitted toInt.J.Syst.Evol.Microbiol.58:2898-2903.
2007
·1.L Liu,C-Y Jiang,X-Y Liu,J-F Wu,J-G Han,S-J Liu.2007.Engineering plant-microbe symbiosis for rhizoremediation of chloronitroaromatic pollutants with Comamonas sp.strain CNB-1.Environ.Microbiol.9:465-473
·2.X-Y Liu,B-J Wang,C-Y Jiang,and S-J Liu.2007.Micrococcus flavus sp.nov.,isolated from activated sludge in a bioreactor.Int.J.Syst.Evol.Microbiol.57:66-69
·3.Y Yang,H-L Cui,P-J Zhou and S-J Liu.2007.Haloarcula amylolytica sp.nov.,an extremely halophilic archaeon isolated from Aibi salt lake in Xin-Jiang,China.Int.J.Syst.Evol.Microbiol.57:103-106
·4.M T Chaudhry,Y Huang,X-H Shen,A Poetsch,C-Y Jiang,S-J Liu.2007.Genome-wide investigation of aromatic acid transport in Corynebacterium glutamicum.Microbiology(SGM)153:857-865
·5.Z-W Chen,Y-Y Liu,J-F Wu,Q.She,C-Y Jiang and S-J Liu.2007.Genetic diversity and identification of novel bacterial sulfur oxygenase reductase genes from gold-bioleaching reactor.Appl.Microbiol.Biotechnol.74:688-698
·6.Lei Liu,Jian-Feng Wu,Ying-Fei Ma,Sheng-Yue Wang,Guo-Ping Zhao,and Shuang-Jiang Liu.2007.A novel deaminase involved in chloronitrobenzene and nitrobenzene degradation in Comamonas sp.strain CNB-1.J.Bacteriol.189:2677-2682
·7.R.Wang,Y-J Yin,F Wang,M Li,J Feng,H-M Zhang,S-J Liu,W-R Chang.2007.Crystal structures and site-directed mutagenesis of a mycothiol-dependent enzyme reveal a novel folding and molecular basis for mycothiol-mediated maleylpyruvate isomerization.J.Biol.Chem.282:16288-15294
·8.Y-F Ma,J-F Wu,S-Y Wang,C-Y Jiang,Y Zhang,S-W Qi,L Liu,G-P Zhao,S-J Liu.2007.Nucleotide sequence of plasmid pCNB1 from Comamonas sp.strain CNB-1 reveals novel genetic organization and evolution for 4-chloronitrobenzene degradation.Appl.Environ.Microbiol.73:4477-4483
·9.Yun Zhang,Ying-Fei Ma,Su-Wei Qi,Bo Meng,Muhammad Tausif Chaudhry,Si-Qi Liu,Shuang-Jiang Liu.2007.Responses to arsenate stress by Comamonas sp.strain CNB-1 at genetic and proteomic levels.Microbiology.153:3713-3721
·10.S-W Qi,M T Chaudhry,Y Zhang,B Meng,Y Huang,K.-X.Zhao,A.Poetsch,C-Y Jiang,S Liu,and S-J Liu.2007.Comparative proteomes of Corynebacterium glutamicum grown on aromatic compounds revealed novel proteins involved in aromatic degradation and a clear link between aromatic catabolism and gluconeogenesis via fructose-1,6-bisphosphatase.Proteomics7:3775-87
2006
·1.Jie Feng,Hong-Can Liu,Jin-Fang Chu,Ji-An Tang,Shuang-Jiang Liu 2006.Genetic cloning and functional expression in Escherichia coli of an archaerhodopsin gene from Halorubrum xinjiangense.Extremophiles.10:29-33
·2.C.-Y.Jiang,X.Dai,B.-J.Wang,Y.-G.Zhou,and S.-J.Liu.2006.Roseomonas lacus sp.nov.,a bacterium isolated from freshwater lake sediment.Int.J.Syst.Evol.Microbiol.56:25-28
·3.X.Dai,B.-J.Wang,Q.-X.Yang,N.-Z.Jiao and S.-J.Liu.2006.Yangia pacifica gen.nov.,sp.nov.,a novel member of the Roseobacter clade from coastal sediment of East China Sea,Int.J.Syst.Evol.Microbiol.56:529-533
·4.J-F.Wu,C-Y Jiang,B-J Wang,Y-F Ma,Z-P Liu,S-J Liu 2006.A novel partial reductive pathway for 4-chloronitrobenzene and nitrobenzene degradation in Comamonas strain CNB-1.Appl.Environ.Microbiol.72:1759-1765
·5.J Feng,Y Che,J Milse,Y-J Yin,L Liu,C Rückert,X-H Shen,S-W Qi,J Kalinowski,S-J Liu.2006.The gene ncgl2918 encodes a novel maleylpyruvate isomerase that needs mycothiol as cofactor and links mycothiol biosynthesis and gentisate assimilation in Corynebacterium glutamicum.J.Biol.Chem.281:10778-10785
·6.H-L Cui,D Tohty,P-J Zhou,S-J Liu.2006.Haloterrigena longa sp.nov.and Haloterrigena limicola sp.nov.,two extremely halophilic archaea isolated from salt lake.Int.J.Syst.Evol.Microbiol.56:1837-1840.
·7.X-Y Liu,B-J Wang,C-Y Jiang,and S-J Liu.2006.Paracoccus sulfuroxidans sp.nov.,a sulfur oxidizer from activated sludge.Int.J.Syst.Evol.Microbiol.56:2693-2695
·8.Y Huang,K-X Zhao,X-H Shen,M T Chaudhry,C-Y Jiang,S-J Liu.2006.Genetic characterization of resorcinol catabolic pathway in Corynebacterium glutamicum.Appl.Environ.Microbiol.72:7238-7245
2005
·1.J-F Wu,C-W Sun,C-Y Jiang,Z-P Liu,and S-J Liu 2005.A novel 2-aminophenol 1,6-dioxygenase involved in the degradation of p-chloronitrobenzene by Comamonas strain CNB-1:purification,properties,genetic cloning and expression in Escherichia coli.Arch.Microbiol.183:1-8.
·2.X-H Shen and S-J Liu 2005.Key enzymes of the protocatechuate branch of theb–ketoadipate pathway for aromatic degradation in Corynebacterium glutamicum.Science in China.48:241-249.
·3.Z-W Chen,C-Y Jiang,Q She,S-J Liu,P-J Zhou 2005.Key role of Cysteine Residues in catalysis and Subcellular Localization of Sulfur Oxygenase Reductase of Acidianus tengchongensis.Appl.Environ.Microbiol.2005 71:621-628
·4.X-H Shen,C-Y Jiang,Y Huang,Z-P Liu,S-J Liu 2005.Functional identification of novel genes involved in the glutathione-independent gentisate pathway in Corynebacterium glutamicum.Appl.Environ.Microbiol.2005 71:3442-3452
·5.X.Dai,Y.-N.Wang,B.-J.Wang,S.-J.Liu and Y.G.Zhou 2005.Planomicrobium chinense sp.nov.,isolated from coastal sediment,and transfer of Planococcus psychrophilus and Planococcus alkanoclasticus to Planomicrobium as Planomicrobium psychrophilum comb.nov.and Planomicrobium alkanoclasticum comb.nov.Int.J.Syst.Evol.Microbiol.55:699-702.
·6.Zhi-Pei Liu,Bao-Jun Wang,Ying-Hao Liu,and Shuang-Jiang Liu 2005.Novosphingobium taihuense sp.nov.a novel aromatic compound-degrading bacterium isolated from Taihu Lake,China.Int.J.Syst.Evol.Microbiol.55:1229-1232.
·7.Zhi-Pei Liu,Bao-Jun Wang,Shuang-Jiang Liu and Ying-Hao Liu 2005.Asticcacaulis taihuensis sp.nov.,a new stalked bacterium isolated from Taihu Lake,China.Int.J.Syst.Evol.Microbiol.55:1239-1242.
·8.Xue-Wei Xu,Pei-Gen Ren,Shuang-Jiang Liu,Min Wu,and Pei-Jin Zhou 2005 Natrinema altunense sp.nov.,an extremely halophilic archaeon isolated from a salt lake in Altun Mountain in Xinjiang,China.Int J Syst Evol Microbiol,55:1311-1314.
2004
·1.J.Feng,P.Zhou,and S.-J.Liu 2004.Halorubrum xingjiangense sp.nov.,a novel halophile isolated from saline lakes in China.Int.J.Syst.Evol.Microbiol.54:1789-1791
·2.X.Shen,Z.Liu,S.-J.Liu 2004.Functional identification of the gene locus(ncg12319)and characterization of catechol 1,2-dioxygenase in Corynebacterium glutamicum Biotechnol.Lett.26:575-580.
·3.Y.-T.Hu,P.-J.Zhou,Y.-G.Zhou,Z.-H.Liu and S.-J.Liu 2004.Saccharothrix xinjiangensis sp.nov.,a pyrene-degrading actinomycete isolated from Tianchi lake,Xinjiang,China.Int.J.Syst.Evol.Microbiol.54:2091-2094.
2003
·1.Demin Zhang,Huifang Yang,Wei Zhang,Zhiyong Huang,and Shuang-Jiang Liu.Rhodocista pekingensis sp.nov.,a cyst-forming phototrophic bacterium from a municipal wastewater treatment plant.Int J Syst Evol Microbiol,2003;53:1111-1114.
·2.Cui-wei Sun,Zhi-wei Chen,Zheng-guo He,Pei-jin Zhou,Shuang-Jiang Liu.2003.Purification and properties of the sulfur oxygenase/reductase from the acidothermophilic archaeon,Acidianus strain S5.Extremophiles 7,131-134
2002
·1.D.Zhang,H.Yang,Z.Huang,W.Zhang,and S.J.Liu.Rhodopseudomonas faecalis sp.nov.,a phototrophic bacterium isolated from an anaerobic reactor that digests chicken faeces.Int J Syst Evol Microbiol,2002;52:2055-2060.
·2.Z.Liu,H.Yang,Z.Huang,P.Zhou,and S.-J.Liu.Degradation of aniline by newly isolated,extremely aniline-tolerant Delftia sp.AN3.Appl.Microbiol.Biotechnol.2002,58:679-682.
·3.Lutke-Eversloh,T;Fischer,A;Remminghorst,U;Kawada,J;Marchessault,RH;Bogershausen,A;Kalwei,M;Eckert,H;Reichelt,R;Liu,SJ;Steinbuchel,A:Biosynthesis of novel thermoplastic polythioesters by engineered Escherichia coli Nature Materials,2002,1:236-240
2000
·1.Z.G.He,Y.Li,P.Zhou,S.-J.Liu.Cloning and heterologous expression of a sulfur oxygenase/reductase from the thermoacidophilic archaeon,Acidianus sp.S5 in Escherichia coli FEMS Microbiol.Lett.2000,193:217-221
·2.Shuang-jiang Liu and Alexander Steinbüchel A Novel Genetically Engineered Pathway for Synthesis of poly(hydroxyalkanoic acid)in Escherichia coli Applied Environmental Microbiology,2000,(66):739-743
·3.S.-J.Liu.A.Steinbüchel Exploitation of butyrate kinase and phosphotransbutyrylase from Clostridium acetobutylicum for the in vitro biosynthesis of poly(hydroxyalkanoic acid)Appl Microbiol Biotechnol,2000,(53):545-55
中文论文:
[1]赵克新,黄燕,刘双江.谷氨酸棒杆菌原儿茶酸途径的调控研究[A]..[C].:,2008:358.
[2]尹雅洁,刘双江.高G+C%,革兰氏阳性细菌中mycothiol及其相关基因研究[A]..[C].:,2008:222.
[3]李唐,刘双江.谷氨酸棒杆菌中对甲酚降解途径分子机制的研究[A]..[C].:,2011:4.
[4]郭鹏,刘双江.拟除虫菊酯降解菌JZ-2的分离鉴定、降解特性及菊酯水解酶的纯化和特性研究[A]..[C].:,2011:7-8.
[5]刘志培,贾省芬,王保军,刘双江.磷化氢含量与某些环境因子的关系[A].张洪勋,庄绪亮.气象出版社[C].:气象出版社,2003:67-68-69-70-71-72-73-74.
[6]李梅,刘双江,梁栋材,常文瑞.硫氧化还原酶的表达、纯化及初步晶体学研究[A]..[C].:,2004:107.
[7]刘兴宇,吴建峰,戴欣,王保军,姜成英,赵可新,刘双江.微生物降解硝基芳烃化合物的物种多样性及其代谢途径[A].李迪.[C].:,2005:98-99.
[8]刘双江,沈锡辉,黄燕,亓苏伟,M.Tausif Chaudhry,冯婕,尹雅洁,姜成英.谷氨酸棒杆菌(Corynebacterium glutamicum)降解芳香化合物的功能基因组学[A]..[C].:,2006:30.
[9]刘兴宇,王保,戴欣,姜成英,吴建峰,赵克辛,刘双江.高效含氮芳烃类物质降解反应器的构建及菌群动态变化[A]..[C].:,2006:151.
[10]刘磊,李习武,刘双江,刘志培.一株降解多环芳烃的菌株Gordonia sp.He~4的分离鉴定及其在菲污染土壤修复过程中的动态变化[A].王如松.[C].:,2006:315.
[11]刘双江.从未培养微生物谈起——对微生物分离培养技术、环境元基因组等研究的思考[A]..[C].:,2007:3.
[12]陈志伟,姜成英,刘双江.腾冲嗜酸两性菌硫氧化还原酶分子结构中铁原子结合位点的新特征[J].科学通报,2009,(1).
[13]朱颖旻,许铭翾,刘庆华,夏海洋,刘双江,覃重军.一株动性球菌ZOYM的初步鉴定及其内源性质粒pPCZ1和pPCZ2的分析[J].微生物学通报,2009,(9).
[14]王海燕,周岳溪,戴欣,柴延丽,蒋进元,刘双江.16SrDNA克隆文库方法分析MDAT-IAT同步脱氮除磷系统细菌多样性研究[J].环境科学学报,2006,(6).
[15]崔恒林,杨勇,迪丽拜尔·托乎提,周培瑾,刘双江.新疆两盐湖可培养嗜盐古菌多样性研究[J].微生物学报,2006,(2).
[16]刘志培,王宝军,贾省芬,刘双江.样品磷化氢含量与某些微生物群落及酶活的关系[J].微生物学报,2006,(4).
[17]刘磊,李习武,刘双江,刘志培.降解多环芳烃的菌株Gordonia sp.He4的分离鉴定及其在菲污染土壤修复过程中的动态变化[J].环境科学,2007,(3).
[18]张涛,刘双江,刘志培.微生物降解对氯苯胺的一条新代谢途径[J].微生物学报,2007,(1).
[19]黄玲,李习武,李旭东,刘双江,刘志培,谭周亮.应用QC-PCR技术研究高效菌株Rhodococcus ruber Em1在废水处理中的作用[J].微生物学报,2007,(2).
[20]刘艳阳,陈志伟,姜成英,刘双江.一株嗜酸化能异养菌Acidiphilium sp.的分离鉴定及其对Fe(Ⅲ)代谢的研究[J].微生物学报,2007,(2).
[21]刘磊,刘志培,吴建峰,刘兴宇,王保军,刘双江.氯代硝基苯降解菌Comamonas sp.strain CNB-1对污染土壤生物修复作用的研究[J].环境科学学报,2007,(4).
[22]应娇妍,杨苏声,刘双江,姜成英.丛毛单胞菌CNB-1合成PHA及相关基因的研究[J].微生物学报,2007,(4).
[23]王保军,刘缨,姜嘉彤,刘斌,刘双江,张佳月.蝎子肠道内微生物多样性研究[J].微生物学报,2007,(5).
[24]刘兴宇,王保军,赵克新,刘磊,姜成英,刘双江.处理含氮芳烃废水SBR生物反应器细菌多样性研究[J].环境科学,2008,(9).
[25]扈玉婷,任凤华,周培瑾,夏敏,刘双江.一株分离自新疆天池寡营养环境的糖丝菌(Saccharothrix sp PYX-6)降解芘的特性[J].科学通报,2003,(16).
[26]刘双江,Tina Lütke-Eversloh,Alexander Steinbüchel.重组大肠杆菌合成聚(3-巯基丙酸)和聚(3-羟基丁酸-3-巯基丙酸)的研究(英文)[J].生物工程学报,2003,(2).
[27]刘志培,贾省芬,俞志明,刘双江.新型异养氨氧化菌的分离鉴定及氨氧化特性[J].环境污染与防治,2005,(5).
[28]李习武,刘志培,刘双江.生物乳化剂产生菌及其产乳化剂条件初步研究[J].微生物学通报,2003,(6).
[29]吴建峰,沈锡辉,周宇光,刘双江.一株降解对氯硝基苯的Comamonas sp.CNB1的分离鉴定及其降解特性[J].微生物学报,2004,(1).
[30]刘双江.富养罗尔斯通氏菌菌株PHB“泄漏”机理的初探[J].微生物学报,2004,(1).
[31]李朝,贾省芬,刘志培,刘双江.红球菌J-5菌株降解聚乙烯醇的研究[J].中国环境科学,2004,(2).
[32]沈锡辉,刘志培,王保军,刘双江.苯酚降解菌红球菌PNAN5菌株(Rhodococcussp.strain PNAN5)的分离鉴定、降解特性及其开环双加氧酶性质研究[J].环境科学学报,2004,(3).
[33]张伟,姜成英,戴欣,刘双江.北京红篓菌合成聚羟基烷酸的研究[J].微生物学通报,2004,(1).
[34]张伟,姜成英,戴欣,刘双江.北京红篓菌聚羟基烷酸合成酶基因的克隆与表达[J].微生物学报,2004,(3).
[35]李习武,刘志培,刘双江.新型复合生物乳化剂的性质及其在多环芳烃降解中的作用[J].微生物学报,2004,(3).
[36]陈志伟,姜成英,刘双江.云南和广东部分热泉Alicyclobacillus分布及系统发育[J].微生物学通报,2004,(3).
[37]王亚南,王保军,戴欣,焦念志,彭志英,刘双江.近海养虾场底泥中产芽孢细菌的生态特征[J].应用与环境生物学报,2004,(4).
[38]刘志培,刘双江.硝化作用微生物的分子生物学研究进展[J].应用与环境生物学报,2004,(4).
[39]刘志培,贾省芬,王保军,刘双江.环境中磷化氢的含量差异及其影响因素[J].环境科学学报,2004,(5).
[40]王亚南,王保军,戴欣,焦念志,彭志英,刘双江.海水养殖场沉积物中硝酸盐还原菌种群分析[J].微生物学通报,2004,(6).
[41]王亚南,彭志英,刘双江.养殖场底泥中芽孢杆菌属细菌的生态学研究[J].湛江海洋大学学报,2004,(4).
[42]沈锡辉,刘双江.谷氨酸棒杆菌中芳香化合物降解的β-酮己二酸途径中原儿茶酸分支关键酶的鉴定[J].中国科学C辑:生命科学,2004,(6).
[43]任华峰,李淑芹,刘双江,刘志培.一株对氯苯胺降解菌的分离鉴定及其降解特性[J].环境科学,2005,(1).
[44]王亚南,王保军,戴欣,焦念志,彭志英,刘双江.海水养殖场底泥中转化硫和磷化合物的微生物及其多样性[J].环境科学,2005,(2).
[45]戴欣,王保军,黄燕,张平,刘双江.普通和稀释培养基研究太湖沉积物可培养细菌的多样性[J].微生物学报,2005,(2).
[46]黄志勇,杨惠芳,刘双江.沼泽红假单胞菌H3对酸性红B_(2GL)染料的厌氧脱色和降解作用[J].环境科学学报,1999,(3).
[47]刘双江.需钠弧菌(Vibrio natriegens)合成聚羟基丁酸的研究[J].生物工程学报,2002,(5).
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项目:
国家863项目“微生物降解基因资源的收集和开发利用”和“谷氨酸棒杆菌芳烃化合物代谢网络及其调控”
国家自然科学基金重点项目“氯代硝基苯类化合物的微生物降解途径和机理的研究”
国家自然科学基金面上项目“微生物降解芳烃化合物过程中转运蛋白及其功能的研究”
中国科学院创新重大项目“长江中下游湖泊富营养化”
中国科学院创新重要方向性项目“污染土壤微生物修复技术的研究”、“水环境污染的生物监控和修复技术及应用”。
国家杰出青年基金获得者,中科院“百人计划”入选者,中国知识产权研究会理事
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